Lingjie Meng

Lingjie Meng

Assistant Professor

Kyoto University

Ph.D. (Sc.)

About me

Hi!

The long-term goal of my research is to understand the diversity, ecology, and evolution of viruses, which I believe are three deeply overlapping topics. My research begins with computational data-driven analysis and field observations (also my current stage), and ultimately, I hope to progress to molecular biology experiments and model validation in my future career.

Specifically, I am currently working on giant viruses at Ogata lab (i.e., the viral phylum "Nucleocytoviricota") in the global marine ecosystem and to find evidence of how these viruses influence the evolution of their eukaryotic hosts. I also expanded the known diversity of giant viruses by discovering a new viral phylum, "Mirusviricota," which broadened my research interest to include all dsDNA viruses.

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Featured Papers

  • Lingjie Meng, Tom O. Delmont, Morgan Gaïa, Eric Pelletier, Antonio Fernàndez-Guerra, Samuel Chaffron, Junyi Wu, Hiroto Kaneko, Hisashi Endo, Hiroyuki Ogata. (2023). Genomic adaptation of giant viruses in polar oceans. Nature Communications, 14: 6233.
    Giant viruses, despite not being defined as 'life', possess large number of genes. Previous research has confirmed that marine giant viruses tend to be endemic, which inspires me to work on the environmental adaptation of giant viruses. In this study, it is suggested that giant viruses have adapted to polar environments through changes in their gene repertoire, and their adaptation mechanism may differ from others. However, current research remains at the hypothetical stage, and especially since there are many unexplained genes in viruses, a definitive virus adaptation mechanism has not been identified.

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